Oral and Craniofacial Sciences Faculty

Sarah Dallas, Ph.D.





















Recent Publications (More articles at PubMed)

(Note: Maiden name = Minter)

Lu, Y, Yuan B, Qin C, Cao Z, Xie, Y, Dallas, SL, D McKee M, Drezner MK, Bonewald LF, Feng JQ (2011). The biological function of DMP1 in Osteocyte Maturation is Mediated by its 57kDa C-terminal Fragment. J. Bone. Miner. Research 26(2):331-40.

Dallas SL and Bonewald LF (2010). Dynamics of the transition from osteoblast to osteocyte. Ann. NY Acad. Sci 1192(1): 437-443.

Dallas SL, Veno PA, Rosser JL, Barragan-Adjemian, C, Rowe, DW, Kalajzic, I, Bonewald, LF. (2009). Time Lapse Imaging Techniques for Comparison of Mineralization Dynamics in Primary Murine Osteoblasts and the Late Osteoblast/ Early Osteocyte-like Cell Line MLO-A5. Cells Tissues Organs. 2009;189(1-4):6-11. PMCID: PMC2824180.

Hadfield KD, Rock CF, Inkson CA, Dallas SL, Sudre L, Wallis GA, Boot-Handford RP, Canfield AE. (2008). HtrA1 Inhibits Mineral Deposition by Osteoblasts: Requirement for the protease and PDZ domains. J Biol Chem. 283(9):5928-38.

Chen Q, Sivakumar P, Barley C, Peters DM, Gomes RR, Farach-Carson MC, Dallas SL. (2007) Potential role for heparan sulfate proteoglycans in regulation of transforming growth factor-beta (TGF-beta) by modulating assembly of latent TGF-beta-binding protein-1. J Biol Chem. 7;282:26418-30.

Huffman NT, Keightley JA, Chaoying C, Midura RJ, Lovitch D, Veno PA, Dallas SL, Gorski JP (2007). Association of specific proteolytic processing of bone sialoprotein and bone acidic glycoprotein-75 with mineralization within biomineralization foci. J Biol Chem. 282(36):26002-13.

Lu, Y, Ye,L., Xie, Y., Zhang, S., Yu, S., McKee, MD., Li, Y., Eick, JD., Dallas, SL., Feng, JQ. (2007). Rescue of odontogenesis in Dmp1-deficient mice by targeted re-expression of DMP1 reveals roles for DMP1 in early odontogenesis and dentin apposition in vivo. Developmental Biology. 303(1):191-201.

Chaudhry, SS., Cain, SA., Morgan, A., Dallas, SL., Shuttleworth, CA., Kielty, CM. (2007). Fibrillin-1 regulates the bioavailability of TGFβ1. J Cell Biol. 176(3):355-67.

Dallas SL. Dynamics of bone extracellular matrix assembly and mineralization. J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):370-1.

Xiao Z, Zhang S, Malios J, Zhou G, Magenheimer BS, Guo D, Dallas SL, Maser R, Calvet JP, Bonewald L, Quarles LD. (2006). Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and runx2 expression. J Biol Chem. 281(41):30884-95.

Sivakumar P., Czirok A., Rongish BJ., Divakara VP., Wang YP., Dallas SL. (2006). New Insights into Extracellular Matrix Assembly and Reorganization from Dynamic Imaging of Extracellular Matrix Proteins in Living Osteoblasts. J. Cell Sci. 119(7):1350-60.

Dallas SL., Sivakumar P., Jones CJP., Chen Q, Peters DM, Mosher DF, Humphries MJ, Kielty CM (2005). Fibronectin Regulates Latent TGFβ by Controlling Matrix Assembly of Latent TGFβ Binding Protein-1. J. Biol Chem. 280(19):18871-80.

Ye L, Mishina Y, Chen D, Huang H, Dallas SL, Dallas MR, Sivakumar P, Kunieda T, Tsutsui TW, Boskey A, Bonewald LF, Feng JO (2005). Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J. Biol. Chem 280: 6197-6203.

Dallas SL., Zhao S., Cramer S., Chen Z., Peehl DM., Bonewald LF (2005). Preferential Production of the Latent Transforming Growth Factor Beta-2 by Prostatic Epithelial Cells and its Activation by Prostate-Specific Antigen. J. Cell Physiol ;202(2):361-70.

Corchero J, Martin-Partido G, Dallas SL, Fernandez –Salguero PM (2004). Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor beta binding protein-1. Int. J. Exp. Pathol 85: 295-302.

Dvorak MM., Siddiqua A., Ward DT., Carter DH., Dallas SL., Nemeth EF, Riccardi D. (2004). Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones. Proc Natl. Acad Sci, USA: 101:5140-5145.

Santiago-Josefat B., Navarro SM., Dallas SL., Fernandez-Salguero, PM (2004)-Overexpression of latent transforming growth factor-β binding protein 1 (LTBP-1) in dioxin receptor-null mouse embryo fibroblasts. J. Cell Sci 117: 849-859.

Bonewald LF, Harris SE, Rosser J, Dallas MR, Dallas SL, Camacho NP, Boyan B, Boskey A (2003). Von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation. Calcif Tissue Int: 72(5):537-47.

Feng JQ, Zhang J, Dallas SL, Lu Y, Chen S, Tan X, Owen M, Harris SE, and MacDougall M. (2002) Dentin Matrix Protein-1, a Target Molecule for Cbfa 1 in Bone, is a Unique Bone Marker gene. J. Bone Miner. Res 17(10) 1822-1831.

Dallas SL, Rosser JL, Mundy GR, Bonewald LF (2002). Proteolysis of latent-TGFbeta binding protein-1 by osteoclasts - a cellular mechanism for release of TGFbeta from bone matrix.
J Biol Chem. 277(24):21352-60.

Michigami T, Shimuzu N, Williams PJ, Niewolna M, Dallas SL, Mundy GR, Yoneda TY (2000). Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4) beta(1) integrin enhances production of osteoclast-stimulating activity. Blood 2000 96(5): 1953-60.

Oyajobi BO, Deng J, Dallas SL, Jenson HB, Mundy GR, Gao SJ (2000). Absence of Herpesvirus sequences in the 5T murine model of human myeloma. Br. J. Hematol. 109(2): 413-419.

Dallas SL, Keene DR, Bruder S, Saharinen J, Sakai LY, Mundy GR, Bonewald LF (2000). Role of the latent transforming growth factor beta binding protein-1 in fibrillin-containing microfibrils in bone cells in vitro and in vivo. J. Bone Miner. Res. 15(1): 68-81.

Hentunen TA, Choi SJ, Boyce BF, Dallas MR, Dallas SL, Sheong GL, Roodman GD (2000). A murine model of inflammatory bone disease. Bone 26(2): 183-188.

Dallas SL, Garrett IR, Oyajobi BO, Dallas MR, Boyce BF, Bauss F, Radl J, Mundy GR (1999). Ibandronate reduces osteolytic lesions but not tumor burden in a murine model of myeloma bone disease. Blood. 93(5): 1697-1706.

Pedrozo HA, Schwartz Z, Gomez R, Ornoy A, Xin-Sheng W, Dallas SL, Bonewald LF, Dean DD and Boyan BD (1998). Growth plate chondrocytes store latent TGF in their matrix through latent TGF binding protein-1. J. Cell Physiol. 177(2):343-54.

Garrett IR, Dallas SL, Radl J, Mundy GR (1997). A murine model of myeloma bone disease. Bone 20(6): 515-520.

Chen D, Harris MA, Rossini G, Dunstan CR, Dallas SL, Feng JQ, Mundy GR (1997). Bone morphogenetic protein-2 (BMP-2) enhances BMP-3, BMP-4 and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts. Calcif. Tissue Int.

Dallas SL, Miyazono K, Skerry TM, Mundy GR, Bonewald LF (1995). Dual role for the latent TGF binding protein (LTBP) in storage of latent TGF in the extracellular matrix and as a structural matrix protein. J. Cell Biol. 131: 539-549.

Harris SE, Bonewald LF, Harris MA, Sabatini M, Dallas SL, Feng JQ, Ghosh-Choudhury N, Wozney J, Mundy GR (1994) Effects of TGF on bone nodule formation and expression of bone morphogenetic protein-2, osteocalcin, osteopontin, alkaline phosphatase and type I collagen mRNA in prolonged cultures of fetal rat calvarial osteoblasts. J bone Min Res 9(6) 855-863.

Dallas SL, Park-Snyder S, Miyazono K, Twardzik D, Mundy GR, Bonewald LF (1994) Characterization and autoregulation of latent transforming growth factor  (TGF) complexes in osteoblast-like cells lines: production of a latent complex lacking the latent TGF binding protein (LTBP). J. Biol Chem 269(9) 6815-6821.

Dallas SL, Zaman G, Pead MJ, Lanyon LE (1993) Early Strain-related changes in cultures embryonic chick tibiotarsi parallel those associated with adaptive remodelling in vivo J. Bone Min Res 8(3) 251-259.

Zaman G, Dallas SL, Lanyon LE (1992) Cultured embryonic bone shafts show osteogenic responses to mechanical loading. Calcif Tissue Int 51(2): 132-136.

Sarah Dallas, Ph.D.
Lee M. and William Lefkowitz Endowed Professor

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